OPAL: Open-community Profiling Assessment tooL

The explosive growth in taxonomic metagenome profiling methods over the past years has created a need for systematic comparisons using relevant performance criteria. The Open-community Profiling Assessment tooL (OPAL) implements commonly used performance metrics, including those of the first challenge of the initiative for the Critical Assessment of Metagenome Interpretation (CAMI), together with convenient visualizations. In addition, diversity metrics from microbial ecology, run time and memory efficiency measurements, and customizable relative importance of metrics facilitate in-depth performance comparisons.