Relief from nitrogen starvation triggers a transient destabilization of glycolytic mRNAs in Saccharomyces cerevisiae cells

A rapid and transient down-regulation of glycolytic mRNAs was observed after replenishment of nitrogen starved yeast. Glucose sensing, protein elongation, nitrogen metabolism, and TOR signaling are factors affecting glycolytic mRNAs stability via a carbon/nitrogen crosstalk. Destabilization occurs by the general mRNA decay pathway.