Understanding the pathogenic mechanism of ACVR1 mutations in Diffuse Intrinsic Pontine Glioma

A research poster outlining the planned experiments and preliminary results of a research project titled 'Understanding the pathogenic mechanism of ACVR1/ALK2 mutations in Diffuse Intrinsic Pontine Glioma (DIPG)'. The subheadings include BMP signalling mechanisms, epigenetic screening, migration assays and CRISPR-Cas9 knockout of mutant ACVR1.